At this time, there are two styles of studies on itaconate: Irg1−/− macrophages as well as regulatory result of itaconate derivatives. Both of these results ended up complementary and exposed that the regulatory mechanisms of itaconate associated alkylation on Keap1 to activate Nrf2, succinate dehydrogenase inhibition, activating transcription issue 3 https://cdk9in1080246.mybjjblog.com/wedelolactone-for-dummies-43114981